In today’s age of light-speed communication and information dissemination, there’s absolutely no excuse for anyone to miss out on any form of info. Modern broadband internet services blazed a trail towards the highway of knowledge and everyone should make full use of it. In this case, let’s start learning more about Hydronephrosis.
This condition is [...]
The post gives the general scheme of management of a patient coming into the emergency with status asthmaticus..the text gives only a general outline of the principles, the treatment modalities may be different in different parts of the world.the text is also meant to help medicos preparing for the board exam to write answers to [...]
RECENT DIAGNOSIS
Clinicopathological studies that 25% of cases have different diagnosis.
Special proteins like tau,alpha synnuclein play a major role.
Immunohistochemistry:LEWY BODIES –hallmark of parkinsonism
TAU PROTEIN DEPOSITS
Hereditary factors : 13 different loci have been associated.
Oxidative stress,impairment in mitochondrial complex 1 are also responsible.
SITE OF FIRST PATHOLOGICAL CHANGE.
OLFACTORY NUCLEUSà
VAGUS NERVE à
LOWER BRAINSTEM NUCLEIà
AMYGDALAà
SUBSTANTIA NIAGRAà
TEMPORAL LOBE
POSSIBLE GENETIC BASIS.
3 MAIN GENES [...]
Migraine - Definition
“Migraine is a familial disorder characterized by recurrent attacks of headache widely variable in intensity, frequency and duration. Attacks are commonly unilateral and are usually associated with anorexia, nausea and vomiting”
-World Federation of Neurology
Migraine Facts
•Migraine is one of the common causes of recurrent headaches
•According to IHS, migraine constitutes 16% of primary [...]
Peyronie’s disease results from a dense fibrous plaque that forms on the tunica albuginea, causing a curvature of the erect penis. Although the precise etiology of the fibrous plaque is unknown, it is believed that the plaque represents scar tissue resulting from microscopic tears of the tunica albuginea that form during intercourse.
Very dense plaques [...]